Brain TNF and Chronic Pain – BrainImmune We have determined that enhanced expression of the pro-inflammatory cytokine Tumor Necrosis Factor...
Fundamentals
Fundamental aspects of brain-immune interactions
Sex Hormones and Immunoregulation The sexual dimorphism in immune responses in humans is well known; females have more vigorous cellular...
Sympathetic Nervous System – Regulatory T cells Homeostatic control of the immune system is dependent on CD4, FoxP3+, NKT or...
The nervous and immune systems share common functions: both are involved in adapting the body to the environment and in...
Vagus Nerve – Neural-Immune Interface Evidence shows that the central nervous system monitors and modulates the activity of both circulating...
The purinergic signaling system, also known as a ‘purinome’, represents extracellular signaling cascades, which are mediated by Adenosine Triphosphate (ATP)...
Tachykinins – Bone Marrow Hematopoiesis is the development of immune and other blood cells from a small population of stem...
T Cell – Antigen Presenting Cell – Sleep Sleep supports immune defense. In the first half of nocturnal sleep, slow...
Brain-Immune Signaling and Pathogen Recognition The body’s reaction to infections involves the orchestration of multiple systems to effectively initiate, execute...
Abstract Psychological stress plays a role in the pathogenesis of several autoimmune disorders. In this overview, we will describe our...
Neuroimmune Biology – Vasopressin Vasopressin (VP) has emerged in recent years as a very important immunoregulatory peptide of the hypothalamus....
The immune and nervous systems are anatomically and functionally interconnected, this cross-talk is evidenced by the dense innervation – mainly...