Selfishness of the brain and immune systems “I feel exhausted with mental stress and with systemic inflammation, but why?” In...
Beta-Adrenoceptors – Tumor Development Over the last 3 decades, an increasing body of evidence suggests that catecholamine-dependent signalling may represent...
Perispinal Delivery Familiarity with the anatomy and physiology of the cerebrospinal venous system (CSVS) is necessary to understand the therapeutic...
The Power of Positive Stress Stress is everywhere. In evolutionary terms, given the range of stressful environmental challenges faced, the...
Allergens – Avoidance Behavior The immune system can recognize, assimilate or reject self and non-self components. Indeed, immunological activities vary...
Major Depressive Disorder – Immunoregulation Urbanized societies are suffering an epidemic of chronic inflammatory disorders such as allergies, autoimmunity and...
Th17 have heterogeneous phenotypes and functions, and can have pro- or anti-inflammatory activities. Pathogenic Th17 cells have been associated to...
wAPC – Hardwired Antigen Presenting Cells In many textbooks, predominantly targeting medical students, i.e. anatomy, histology and physiology, or in...
Dysautonomia in Fibromyalgia Fibromyalgia (FM) is a stress-related disorder that predominately affects women. FM’s outstanding clinical features are chronic widespread...
Insulin Resistance – Selfish Brain Over the last century insulin resistance has been found in many physiological and disease states....
Stress-Induced Th2 Shift – Thyroid Autoimmunity Thyroid autoimmunity may manifest clinically as chronic autoimmune or Hashimoto’s thyroiditis (HT) and its...
Energy Regulation – Chronic Inflammatory Diseases The general meaning of the systemic response in inflammatory diseases is not well understood....