A hierarchical cytokines framework Extensive genome-wide association and epidemiological studies have shed light on the causes of chronic inflammatory diseases...
Beta2-Adrenergic Agonists – Parkinson’s Disease Parkinson’s disease (PD) affects 0.1-0.2% of the general population with increasing prevalence with age, and...
For many years, people with fibromyalgia endured a double ordeal. They suffered from widespread pain, exhaustion, sleep disturbances, cognitive fog,...
IL-17: A Promising Therapeutic Target Since the discovery of T helper 17 (Th17) cells, an increasing body of evidence indicates...
Neural Meshwork Resembling Glass Fishing Float The sympathetic neuronal control of immunity in primary and secondary lymphoid organs is exerted...
Targeting Neuroinflammation – Alzheimer’s Disease Compelling new data published online in the journal CNS Drugs documents a substantial and significant...
Alpha-Adrenergic Receptors – Hematopoiesis Hematopoiesis takes place in specialized structures of the bone marrow (BM) called hematopoietic niches. These structures...
Brain Lymphatics – Neuronal Homeostasis A few years ago, we discussed here the discovery of the brain lymphatic system and...
Viable targets – psychiatric disorders – identified The history of pharmacologic therapy for psychiatric disorders is largely one of observation...
Melatonin – Pathogenic Th17 and Regulatory T Cells The central master circadian clock is located in the suprachiasmatic nucleus (SCN)....
Key Factors – COVID-19 Severity The COVID-19 outbreak was first identified in Wuhan, China. Despite the causal agent being closely...
Catecholamines – enterovirus-71 infectivity Outbreaks of Human Enterovirus 71 (EV71) are often reported in Asia. EV71 is responsible for syndromes...