Beta-Blockers Emerge as Beneficial in Early and Triple-Negative Breast Cancer: Reasons Why and the Role of a Sympathetic Overdrive in TNBC Patients
Evidence accumulated over the last 20 years indicates that beta-blockers are beneficial or perhaps even life-saving in early stage breast cancer (BC). Importantly, beta-blockers reduce mortality and have a more pronounced prognostic effect mainly in triple-negative breast cancer...
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STRESS & IMMUNITY
Acid Sensing – Sensory Neurons – Inflammation – BrainImmune Chronic inflammatory conditions, such as rheumatoid arthritis (RA), are characterized by continuous pain and RA is the most frequent form of inflammatory joint disease in the...
Endogenous Catecholamines in Immune Cells: Discovery, Functions And Clinical Potential as Therapeutic Targets
Endogenous catecholamines in immune cells – BrainImmune The catecholamines dopamine, noradrenaline and adrenaline are well established neurotransmitters and neurohormones. Sympathoadrenergic pathways are pivotal to the communication between the nervous system and the immune system, and...
Sex Steroids and Autoimmune Disease – BrainImmune Females display an increased incidence of autoimmune diseases, with a sexual dimorphism in the immune response. The autoimmune diseases involve both genetic and...
Inflammation is the body’s response to insults. During inflammation, various inflammatory cells are activated to release cytokines and mediators and orchestrate progressing inflammation. Clinically, pneumonia and acute respiratory distress syndrome...
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