sympathetic innervation and immune system

Sympathetic Nerves via β2-adrenoceptor Signaling Generate Circadian Rhythms and Govern Lymphocyte Recirculation in Lymph Nodes

Sympathetic Nerves via β2-adrenoceptor Signaling Generate Circadian Rhythms and Govern Lymphocyte Recirculation in Lymph Nodes

A new study, published in the Journal of Experimental Medicine (JEM), indicates that in mice, the sympathetic nervous system (SNS) innervation, through β2-adrenergic receptors activation controls the circadian dynamics and traffic of lymphocytes through the lymph nodes (LNs). Both primary and secondary lymphoid organs are heavily innervated, mostly by the peripheral sympathetic nerves. Thus, locally […]