stress and inflammation

Lifetime Adversity Is Associated With Inflammation and Elevated CRP Levels

Lifetime Adversity Is Associated With Inflammation and Elevated CRP Levels

A recent study published in Brain, Behavior and Immunity suggests that adversity during childhood and trauma during adulthood are associated with elevated high sensitivity C-reactive protein (hsCRP). This is perhaps the first large population-based study to assess the connection between adulthood trauma exposure and inflammation. Over 11,000 adults ranging from age 59 to 79 years […]

Large Population Study Links Stress in Middle Age Women to Dementia and Alzheimer’s Risk Decades Later

Large Population Study Links Stress in Middle Age Women to Dementia and Alzheimer’s Risk Decades Later

A Swedish study, published in the August 2013 online issue of BMJ Open indicates that a higher number of psychosocial stressors in middle-aged women were associated with increased risk of dementia and Alzheimer’s disease (AD) decades later in life. This is perhaps the first population study on the relationship between midlife stressors and increased risk […]

Stress and Worrying Affect Short-Term Fluctuations in Rheumatoid Arthritis Symptoms

Stress and Worrying Affect Short-Term Fluctuations in Rheumatoid Arthritis Symptoms

In the July 2013 issue of Annals of Rheumatic Diseases, Evers et al. report that stress and worrying predict indicators of rheumatoid arthritis disease activity such as fatigue and pain. Psychological stress has been linked to the onset and course of rheumatoid arthritis (RA). While for the juvenile chronic arthritis (JCA), chronic stress appear to […]

Psychological Stress May Promote Inflammation through Expansion of Immature Proinflammatory Monocytes

Psychological Stress May Promote Inflammation through Expansion of Immature Proinflammatory Monocytes

A recent study by Nicole Powell et al. published in the October 8, 2013 issue of PNAS, suggests that stress hormones may contribute to pro-inflammation through selective expansion and/or recruitment of a specific subpopulation of immature, proinflammatory monocytes. In the 1970s and 1980s stress was often considered immunosuppressive. Recent evidence, however, indicates that psychological stress […]

Sarcopenia, the Skeletal Muscle as an Endocrine Organ and Aging

Sarcopenia, the Skeletal Muscle as an Endocrine Organ and Aging

In a recent review, Drs. A. Pratesi, F. Tarantini and M. Di Bari discuss major hormonal and immune mechanisms that drive the age-related decline in muscle quantity and quality. Besides the hormonal factors, the authors outline the role of some skeletal muscles mediators, termed ‘myokines’ that act in an autocrine, paracrine, or ‘hormone-like’ fashion. This […]

Combat-training stress and high pro-inflammatory markers in soldiers linked to increased intestinal permeability and gastrointestinal symptoms

Combat-training stress and high pro-inflammatory markers in soldiers linked to increased intestinal permeability and gastrointestinal symptoms

A study published in the February 2013 issue of Alimentary Pharmacology and Therapeutics reports that soldiers participating in as little as 6 weeks of combat training had high stress; anxiety and depression levels combined with gastrointestinal (GI) symptoms, pro-inflammatory immune activation and increased intestinal permeability. Gastrointestinal symptoms in soldiers are among the most common causes […]

The Role of Immunoregulating Microbes in Stress Resilience

The Role of Immunoregulating Microbes in Stress Resilience

In the March 2013 issue of Evolution, Medicine, and Public Health, Graham Rook et al. review a multitude of epidemiological data to highlight links between sanitation, psychiatric disorders and stress resilience. At the core of this concept is the Hygiene Hypothesis and “Old Friends” mechanism, which suggest that increased sanitation accounts for increases in inflammatory […]

Neurotensin, CRH and Mast Cell Activation: Implications for Stress-Induced Exacerbations of Allergic Diseases

Neurotensin, CRH and Mast Cell Activation: Implications for Stress-Induced Exacerbations of Allergic Diseases

A study published in PLoS One indicates the presence of distinctive interactions between neurotensin (NT), corticotropin-releasing hormone (CRH) and mast cells that may be involved in inflammatory- and/or stress-related diseases. Psychological stress is known to aggravate asthma, migraines and certain autoimmune/inflammatory diseases. Although the mechanisms of stress-induced exacerbations of these conditions are not fully understood, […]

Developmental Changes in the Neuroendocrine/Stress-Immune Interactions: Immunosenescence and Infectious/Inflammatory Disease Risk in the Elderly

Developmental Changes in the Neuroendocrine/Stress-Immune Interactions: Immunosenescence and Infectious/Inflammatory Disease Risk in the Elderly

In a recent review, Kathi Heffner from the Department of Psychiatry, University of Rochester Medical Center, Rochester, New York outlines recent data suggesting that immunosenescence, endocrinosenescence and age-related dysregulation of stress response systems are closely intertwined. Immunosenescence refers to the dysfunction and gradual deterioration of the immune system associated with aging. This overall change in […]

Negative and Competitive Interpersonal Stressors Linked to High Proinflammatory Cytokine Responses

Negative and Competitive Interpersonal Stressors Linked to High Proinflammatory Cytokine Responses

In a recent PNAS study, Jessica Chiang and colleagues from the Department of Psychology, David Geffen School of Medicine, University of California, Los Angeles, investigated the potential importance of negative, competitive and positive daily interactions on inflammatory activity. The authors of this study demonstrate that negative social interactions significantly predicted higher baseline levels of sTNFaRII […]

Page 1 of 212