sex and immunity

Sex Steroids Hormones and Autoimmune Disease Activity

Sex Steroids Hormones and Autoimmune Disease Activity

OVERVIEW ARTICLE Females display an increased incidence of autoimmune diseases, with a sexual dimorphism in the immune response. The autoimmune diseases involve both genetic and environmental factors and the autoimmune process is characterized by the breakdown of tolerance in subjects with genetic susceptibility, with subsequent target (organ-specific and not) injury, that, in turn, elicits repairing […]

Stress Response, Sex and Immunity: the Female Superiority

Stress Response, Sex and Immunity: the Female Superiority

SHORT FEATURES and FACES ARTICLE In this recent perspective, George Chrousos, M.D., discusses some new evidence indicating gender-specific differences in the actions of glucocorticoids and why women are superior to men in dealing with stress and infections. These gender differences are discussed from an evolutionary perspective, including gene network evolution and steroid molecular actions, as […]