psychological stress

Neuroendocrine Immunology in 2014 – What Was Hot and Some Conceptual Trends as Presented on BrainImmune

Neuroendocrine Immunology in 2014 – What Was Hot and Some Conceptual Trends as Presented on BrainImmune

Editorial In 2014 we witnessed a rapid growth of the research and studies at the interface and intersection of neurosciences and immunology. This vast interdisciplinary area, often referred to as neuroendocrine immunology or neuroimmunology, also includes stress-immune interactions that may have complex and multifaceted impact on health and disease. Last year also brought some interesting […]

David Goldstein, Adrenaline, the Inner World and the Scientific Integrative Medicine

David Goldstein, Adrenaline, the Inner World and the Scientific Integrative Medicine

SHORT FEATURES and FACES ARTICLE Dr. Goldstein founded and directs the Clinical Neurocardiology Section at the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland. He is author of several books, including ‘Adrenaline and the Inner World: An Introduction to Scientific Integrative Medicine’, ‘Dysautonomias: A Handbook for Patients’, ‘Stress, Catecholamines, and […]

Immigration and Stress: High Depression and Suicide Attempts Linked To Acculturative Stress in Indiana’s Latino Teens

Immigration and Stress: High Depression and Suicide Attempts Linked To Acculturative Stress in Indiana’s Latino Teens

Recently, a community-based study on the acculturative stress–depression link was presented at the American Public Health Association’s Annual Meeting and Exposition in New Orleans, Louisiana, Nov. 17. The term acculturation, coined in 1880 by John W. Powell refers to the modification of the culture of a group or individual as a result of contact with […]

New Evidence that Stress Mediators Directly Affect Hematopoiesis and Increase Neutrophil and Monocyte Production

New Evidence that Stress Mediators Directly Affect Hematopoiesis and Increase Neutrophil and Monocyte Production

A study published in Nature Medicine suggests that stress mediators may also directly activate hematopoi­etic stem cells (HSCs), which increase proliferation and differentiate into downstream progenitor cells, with the end result of an accelerated neutrophil and monocyte production. Acute stress is known to induce a transient leukocytosis, mostly due to an increase in natural killer […]

Chronic Stress and IL-10/STAT3 Pathway’s Induction

Chronic Stress and IL-10/STAT3 Pathway’s Induction

A study published in Brain, Behavior, and Immunity journal indicates that the interleukin (IL)-10/STAT3 pathway may play a key role in the immunosuppression induced by chronic stress. IL-10 is a major anti-inflammatory cytokine, which possesses potent immunosuppressive actions. Stress mediators, particularly catecholamines (CAs), are potent IL-10 inducers, and in clinical conditions such as brain trauma, […]

Forbes Magazine and Stress Awareness in America

Forbes Magazine and Stress Awareness in America

According to Dr. Robert Pearl, and his recent article in Forbes magazine, psychological stress – a very common problem in America – is often overlooked and represents an issue not properly managed by doctors and the health care system. Moreover, associations of stress with common human diseases are poorly understood by many clinicians and, thus, […]

The Burden of Stress in America 2014 Survey

The Burden of Stress in America 2014 Survey

The Burden of Stress in America’s 2014 survey examined the role of stress in different aspects of Americans’ lives, as part of several events sponsored by the Robert Wood Johnson Foundation. The survey was conducted from March 5 to April 8, 2014 with a sample of 2,505 respondents. The poll was developed by researchers at […]

Magnified Peripheral IL-6 Response Linked To Stress Susceptibility and Higher Risk of Depression

Magnified Peripheral IL-6 Response Linked To Stress Susceptibility and Higher Risk of Depression

A new study published in the Proceedings of the National Academy of Sciences of the USA is perhaps the first to demonstrate that the magnitude of peripheral interleukin (IL)-6 responses preceding stress challenge may confer inter-individual differences in susceptibility or resilience to a subsequent social stressor. Previous research indicates that in humans both major depression […]

Lena Johansson, Stress and Alzheimer’s Risk in Women

Lena Johansson, Stress and Alzheimer’s Risk in Women

SHORT FEATURES and FACES ARTICLE In this recent editorial, Lena Johansson outlines some current concepts and research trends related to the long terms effects of stress and their impact on risk and development of Alzheimer’s disease (AD) in women. Dr. Johansson has authored two population studies – perhaps the first in this area – on […]

A PTSD Mouse Model Links Stress with Acute Heart Injury

A PTSD Mouse Model Links Stress with Acute Heart Injury

In the February 2014 issue of the Proceedings of the National Academy of Sciences of the USA (PNAS) Ji-Hoon Choa and colleagues from the Institute for Systems Biology, Seattle, WA, USA, used an adapted aggressor-exposed social stress mouse model for PTSD to demonstrate genetically associated stress-induced tissue injuries on peripheral organs, including the heart. Posttraumatic […]