neuro immune disease disorders

Sympathetic Dysautonomia in Fibromyalgia: Brief Overview

Sympathetic Dysautonomia in Fibromyalgia: Brief Overview

Evolving Concepts Fibromyalgia (FM) is a stress-related disorder that predominately affects women. FM’s outstanding clinical features are chronic widespread pain, paresthesias, allodynia, fatigue, sleep difficulties and cognitive impairment. Other FM associated symptoms relate to irritable bowel, temporo-mandibular dysfunction and interstitial cystitis [1]. FM pathogenesis has not been elucidated. Our group has proposed dysautonomia as an […]

High Neonatal Monocyte Chemotactic Protein-1 (MCP-1) Levels May Represent an Early Marker of Autism

High Neonatal Monocyte Chemotactic Protein-1 (MCP-1) Levels May Represent an Early Marker of Autism

A study published in the Journal of Neuroinflammation indicates that the chemokine monocyte chemotactic protein-1 (MCP-1) may represent an early marker for ASD. Immune dysregulation and markers of inflammation have been associated with Autism Spectrum Disorder (ASD). Yet, most of the prior studies have used specimens taken after clinical diagnosis, and even with the relatively […]