innervation lymph system

The Nervous System’s Relationship to Immune Events: ‘Broadly Based but Cell-Faced’ – ‘wAPC’ as Hardwired Antigen Presenting Cells

The Nervous System’s Relationship to Immune Events: ‘Broadly Based but Cell-Faced’ – ‘wAPC’ as Hardwired Antigen Presenting Cells

EVOLVING CONCEPTS ARTICLE In many textbooks, predominantly targeting medical students, i.e. anatomy, histology and physiology, or in more specialized areas of interest such as immunology or neurobiology, the innervation of immune organs is still something of a mystery as concerns the peripheral nervous system. One reason may be that the fields of immunology and neurobiology […]

Neural Meshwork Resembling Glass Fishing Float Envelops Antigen Presenting Cells in Lymphoid Organs

Neural Meshwork Resembling Glass Fishing Float Envelops Antigen Presenting Cells in Lymphoid Organs

COMMENTARY ARTICLE on the study by Clemens Wülfing & Hauke S. Günther, Sci Rep, 2015, 5:16866 ‘Dendritic cells and macrophages neurally hard-wired in the lymph node’ The sympathetic neuronal control of immunity in primary and secondary lymphoid organs is exerted through “hard-wired” noradrenergic nerve terminals through the release of norepinephrine that interacts with the immune […]