immune tolerance

IL-35 Contributing to Immune Tolerance in Normal Pregnancy

IL-35 Contributing to Immune Tolerance in Normal Pregnancy

A study published in PLoS One indicates that normal pregnancy is associated with increased levels of interleukin (IL)-35, whereas recurrent spontaneous abortions are linked to low levels of this cytokine, suggesting the involvement of IL-35 in the maintenance of immune tolerance during pregnancy. IL-35, identified in 2007 is a major immunosuppressive and anti-inflammatory cytokine along […]