Hashimoto’s thyroiditis

New Evidence that Th17 Cells Contribute to Hashimoto’s Thyroiditis

New Evidence that Th17 Cells Contribute to Hashimoto’s Thyroiditis

Commentary On the study by K Degertekin et al, Cytokine, 2016, 80:13-7 Circulating Th17 cytokine levels are altered in Hashimoto’s thyroiditis The T helper (Th)1/Th2 paradigm has been used to explain many aspects of immune physiology and several immune-associated pathological conditions. Recent progress in the field has prompted increased focus on other effector T lymphocytes […]

Thyroid Hormone Modulation of Immune Responses in Physiologic and Stressful Conditions: Implications for Thyroid Diseases

Thyroid Hormone Modulation of Immune Responses in Physiologic and Stressful Conditions: Implications for Thyroid Diseases

Overview article Recent evidence indicates the presence of bidirectional interactions between the hypothalamic-pituitary-thyroid (HPT) axis and the immune system. Hypothyroidism leads to a suppression of humoral and cell-mediated immune responses, effects that are often reversed by restoration of the euthyroid state. In accordance, chronic stress induces a decrease in thyroid hormone levels that in turn, […]