fight-or-flight

David Goldstein, Adrenaline, the Inner World and the Scientific Integrative Medicine

David Goldstein, Adrenaline, the Inner World and the Scientific Integrative Medicine

SHORT FEATURES and FACES ARTICLE Dr. Goldstein founded and directs the Clinical Neurocardiology Section at the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland. He is author of several books, including ‘Adrenaline and the Inner World: An Introduction to Scientific Integrative Medicine’, ‘Dysautonomias: A Handbook for Patients’, ‘Stress, Catecholamines, and […]

The Burden of Stress in America 2014 Survey

The Burden of Stress in America 2014 Survey

The Burden of Stress in America’s 2014 survey examined the role of stress in different aspects of Americans’ lives, as part of several events sponsored by the Robert Wood Johnson Foundation. The survey was conducted from March 5 to April 8, 2014 with a sample of 2,505 respondents. The poll was developed by researchers at […]

Richard Kvetnansky – 45 years of Stress Research

Richard Kvetnansky – 45 years of Stress Research

SHORT FEATURES and FACES ARTICLE Richard Kvetnansky, M.D., is the head of the Laboratory of Stress Research at the Institute of Experimental Endocrinology, Slovak Academy of Sciences in Bratislava, Slovakia. He was a director of the Institute for eight years. Dr. Kvetnansky, an experimental endocrinologist, has performed seminal work in the field of the sympathoadrenal […]

The Stress(ed) World and Hans Selye

The Stress(ed) World and Hans Selye

SHORT FEATURES and FACES ARTICLE 80 years after Hans Selye introduced the concept and term ‘stress’ there is a very substantial body of evidence that psychological stress is linked to the pathogenesis of several common human diseases. According to the American Institute of Stress, stress is America’s #1 health problem. Two-thirds of all office visits […]

Stress: From Hans Selye to Paris Hilton

Stress: From Hans Selye to Paris Hilton

SHORT FEATURES and FACES ARTICLE In a recent FASEB editorial, Gerald Weissmann comments on the modern use of the word ‘stress’ and its evolution from Hans Selye’s original definition. According to Weissmann, the Editor-in-Chief of the FASEB journal, Selye first advanced the notion of stress as a generalized response to any insult in 1936, which […]

The Discovery of Adrenaline

The Discovery of Adrenaline

HISTORY OVERVIEWS The first practical discovery of adrenaline by man occurred when one of our ancestral hominids while out for a stroll was unexpectedly surprised by a sabre-toothed tiger. Isolating and naming the compound were not uppermost in our man’s mind at the time and it was not until the late nineteenth century that progress […]

Walter Cannon: Homeostasis, the Fight-or-Flight Response, the Sympathoadrenal System, and the Wisdom of the Body

Walter Cannon: Homeostasis, the Fight-or-Flight Response, the Sympathoadrenal System, and the Wisdom of the Body

HISTORY OVERVIEWS Scientific integrative medicine finds its roots in the seemingly simple but actually enormously difficult issue of how higher organisms maintain their integrity despite the vicissitudes of life. The great French experimentalist of the mid-nineteenth century and prototypical experimentalist, Claude Bernard, propounded its founding concept. Bernard introduced the idea of the “inner world” when […]