Etanercept

Perispinal Delivery of CNS Drugs: From Corning to Perispinal Etanercept

Perispinal Delivery of CNS Drugs: From Corning to Perispinal Etanercept

Evolving Concepts Introduction Familiarity with the anatomy and physiology of the cerebrospinal venous system (CSVS) is necessary to understand the therapeutic potential of perispinal injection for treatment of central nervous system (CNS) disorders [1, 2]. The CSVS is composed of the confluence of the venous systems of the spine and the brain, which together constitute […]

Perispinal Etanercept Improves Neurological Function in Chronic Brain Injury

Perispinal Etanercept Improves Neurological Function in Chronic Brain Injury

A new case report by Tobinick et al. in the May 2014 issue of Clinical Drug Investigation describes striking success with a single perispinal etanercept dose in a patient who sustained brain injury 3 years prior. Multiple reports have shown promise for use of etanercept, a tumor necrosis factor (TNF) inhibitor, in patients with chronic […]