brain superautoantigens

Brain Superautoantigens: Connections between Immune and Neural Repertoires

Brain Superautoantigens: Connections between Immune and Neural Repertoires

Opinion Article Introduction Although human cells express a quasi-infinite number of potential autoantigens, only a limited range of the human “self” antigen library is actually targeted by pathological autoimmunity. Accordingly, the clinical expression of human autoimmunity is essentially restricted to relatively few stereotyped disorders including psoriasis, diabetes, vitiligo, thyroiditis, rheumatoid arthritis and multiple sclerosis. Thus, […]