What’s Hot

short notes on new advances in the field

Adiponectin potentiates Th1 and Th17 immune responses

Adiponectin potentiates Th1 and Th17 immune responses

A new study published in March 2013 issue of the Journal of Immunology identifies a new immunomodulatory effect of adiponectin (APN) – its ability to activate DCs through PLCγ/JNK/NF-κB-signaling pathways and release of proinflammatory cytokines, and to potentiate Th1 and Th17 immune responses. Adiponectin, the most abundant adipokine, is known for its insulin-sensitizing effects, is […]

Cold-Induced Stress May Promote Chlamydia Genital Infection

Cold-Induced Stress May Promote Chlamydia Genital Infection

A recent study by Tesfaye Belay and Anthony Woart from the School of Arts and Sciences, Bluefield State College, Bluefield, WV, is perhaps the first to document a link between cold (weather) stress and the course of Chlamydia trachomatis infection. This common sexually transmitted infection is known to cause severe complications such as pelvic inflammatory […]

Activation of Beta2-Adrenoreceptors Drives T Helper Cell Priming In Favor of IL-17 Responses

Activation of Beta2-Adrenoreceptors Drives T Helper Cell Priming In Favor of IL-17 Responses

In a recent study published in the journal Cytokine, Michela Manni, Richard Granstein and Georges Maestroni, from the Center for Experimental Pathology, Locarno, Switzerland, provide new evidence suggesting that catecholamines, through activation of beta2-adrenoreceptors (ARs) on immune cells, may drive, in certain conditions, Th17 immune responses. The authors report that the beta2-AR agonist salbutamol is […]

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