Stress-Immune News

reports on new advances in the area of stress-immunity interactions

Stress, Immunity and Coronary Artery Disease

Stress, Immunity and Coronary Artery Disease

In this review Roger Ho and colleagues discuss how stress hormones through affecting different components of the immune/inflammatory reaction may in turn contribute to the development of coronary artery disease (CAD). Recent evidence indicates that acute and chronic psychological stress, such as intense anger, low socioeconomic status, work stress, social isolation, depression, anxiety and hostility […]

Substance P Promotes Th17 Phenotype in Generalized Anxiety Disorder

Substance P Promotes Th17 Phenotype in Generalized Anxiety Disorder

A study published in the journal of Clinical Immunology demonstrates that the cytokine profiles in generalized anxiety disorder (GAD) individuals show traits of Th1 and Th2 deficiencies but are associated with a predominant Th17 phenotype, particularly in the presence of substance P (SP). Substance P has been shown to stimulate the inflammatory response, contributing to […]

Stress and Disorders of the Stress System

Stress and Disorders of the Stress System

In this recent review, George Chrousos, M.D., an established expert, working in the stress research area for over 30 years, provides a brief, albeit comprehensive, synthesis of information on the conceptual evolution, and current understanding of homeostasis and stress, and the pathogenic disturbances that are associated with distress. The author discusses the mediators and mechanisms […]

Early Childhood Stress is Associated With Elevated Antibody Levels to Herpes Simplex Virus Type 1 in Adolescence

Early Childhood Stress is Associated With Elevated Antibody Levels to Herpes Simplex Virus Type 1 in Adolescence

A study published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS) indicates that a stressful early childhood history affects the long-term functioning of the immune system, specifically evidenced by a secretion of higher levels of herpes simplex virus (HSV)-antibodies into saliva. The link between psychological stress and […]

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