Editorials and Opinion

BrainImmune short editorials and opinion articles

Brain Superautoantigens: Connections between Immune and Neural Repertoires

Brain Superautoantigens: Connections between Immune and Neural Repertoires

Opinion Article Introduction Although human cells express a quasi-infinite number of potential autoantigens, only a limited range of the human “self” antigen library is actually targeted by pathological autoimmunity. Accordingly, the clinical expression of human autoimmunity is essentially restricted to relatively few stereotyped disorders including psoriasis, diabetes, vitiligo, thyroiditis, rheumatoid arthritis and multiple sclerosis. Thus, […]

Neuroendocrine-Immunology Progress and Development Stories: 2016 in Review

Neuroendocrine-Immunology Progress and Development Stories: 2016 in Review

Editorial Neuroendocrine-immunology has achieved substantial progress and growth over the last year. As the BrainImmune mission is to promote the advancement of this research field, it is becoming a tradition to recapitulate the latest developments in this relatively new interdisciplinary area that bridges neurosciences and immunology. Note that this is not a complete list, but […]

2015 Bringing Some Major Advances in Neuroendocrine Immunology

2015 Bringing Some Major Advances in Neuroendocrine Immunology

Editorial In 2003, the National Institutes of Health (NIH), Bethesda, MD, USA, launched the NIH Roadmap for Medical Research, marking the renaissance in interdisciplinary research, and outlining new perspectives of cutting-edge 21st century work that crosses disciplines. The ‘interdisciplinary research’, as per the Roadmap, was defined as “integrating the analytical strengths of two or more […]

Neuroendocrine Immunology in 2014 – What Was Hot and Some Conceptual Trends as Presented on BrainImmune

Neuroendocrine Immunology in 2014 – What Was Hot and Some Conceptual Trends as Presented on BrainImmune

Editorial In 2014 we witnessed a rapid growth of the research and studies at the interface and intersection of neurosciences and immunology. This vast interdisciplinary area, often referred to as neuroendocrine immunology or neuroimmunology, also includes stress-immune interactions that may have complex and multifaceted impact on health and disease. Last year also brought some interesting […]

Thymus Emergence & Evolution of Immune and Neuroendocrine Systems

Thymus Emergence & Evolution of Immune and Neuroendocrine Systems

Editorials & Opinion Galen (129 – 210 or 216 AD) first described an organ located behind the sternum and named it ‘thymus’ because of its close resemblance with a leaf of the thyme plant. For Galen, the thymus was the ‘seat of soul, eagerness, and fortitude’, and this old misconception most probably explains why some […]

Mainstream Immunology Research and Cultural Separation

Mainstream Immunology Research and Cultural Separation

Editorials & Opinion One of the curious aspects of modern biomedicine is the “cultural separation” of immunology research from neurobiology and physiology research. One can argue that the failure to link the immune system to the brain (and vice versa) has played a role in the immunology’s minimal progress from the bench to the bedside […]