Rainer Straub and the Origin of Chronic Inflammatory Systemic Diseases

Rainer Straub and the Origin of Chronic Inflammatory Systemic Diseases

SHORT FEATURES and FACES ARTICLE Synopsis of the Book The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae by Rainer H Straub Academic Press/Elsevier Chronic inflammatory systemic diseases (CIDs) are a burden to humans because approximately 10% of the population is affected by long-standing chronic inflammatory illness. The numbers would be extensively higher if […]

Insulin Resistance: An Adaptive Program of the Selfish Brain and Immune System

Insulin Resistance: An Adaptive Program of the Selfish Brain and Immune System

Evolving Concepts Over the last century insulin resistance has been found in many physiological and disease states. A few examples are diabetes mellitus, obesity, infection, sepsis, different types of arthritis (including rheumatoid arthritis), systemic lupus erythematosus, ankylosing spondylitis, trauma, painful states such as postoperative pain and migraine, schizophrenia, major depression, and mental stress (reviewed in […]

Evolutionary Medicine, Energy Regulation and the Pathogenesis of Systemic Chronic Inflammatory Diseases

Evolutionary Medicine, Energy Regulation and the Pathogenesis of Systemic Chronic Inflammatory Diseases

Evolving Concepts The general meaning of the systemic response in inflammatory diseases is not well understood. Nor do we know whether the systemic response has any unfavorable role when inflammatory diseases become chronic. We call chronic inflammatory diseases (CIDs) “systemic in nature”, but the significance of these systemic signs and symptoms is not known. In […]