Stress and Cancer: A Link Through the Chinese Cultural Revolution

Stress and Cancer: A Link Through the Chinese Cultural Revolution

Overview Article It is now well recognized that preventive health care requires going beyond the immediate causes of diseases and understanding their fundamental socio-economic determinants. Cancer is one of these diseases that has emerged as the top killer, both physically and economically, surpassing heart disease, in many high-income countries. Does stress contribute to these increasing […]

Biobehavioral Factors, Stress and Cancer Progression: A Contemporary Review

Biobehavioral Factors, Stress and Cancer Progression: A Contemporary Review

In two recent reviews, published in 2011, Erin Costanzo, Anil Sood and Susan Lutgendorf provide a contemporary overview of the major pathways involved in the cross-talk between behavioral factors and the immune system that contribute to cancer development  and progression. The idea that psychological factors may contribute to cancer development and progression is not new. […]

Celebrities, Stress and Cancer

Celebrities, Stress and Cancer

SHORT FEATURES and FACES ARTICLE Recently, several websites have reported that Michael Douglas has been diagnosed with throat cancer. The actor believes a combination of his previous hard-driving lifestyle and the stresses of the past 12 months may have caused the cancer. He tells UK’s Daily Mirror that stress was a major factor: “This type […]

Neuroendocrine-Immunology Progress and Development Stories: 2016 in Review

Neuroendocrine-Immunology Progress and Development Stories: 2016 in Review

Editorial Neuroendocrine-immunology has achieved substantial progress and growth over the last year. As the BrainImmune mission is to promote the advancement of this research field, it is becoming a tradition to recapitulate the latest developments in this relatively new interdisciplinary area that bridges neurosciences and immunology. Note that this is not a complete list, but […]

Beta-Adrenoceptors and Tumor Development: Novel Concepts and Clinical Implications

Beta-Adrenoceptors and Tumor Development: Novel Concepts and Clinical Implications

Evolving Concepts Over the last 3 decades, an increasing body of evidence suggests that catecholamine-dependent signalling may represent a major link between chronic stress and tumor progression. Studies addressing the relationship between stress-activated pathways and cancer progression suggest that stress-induced production of adrenaline and noradrenaline, besides affecting the anti-tumor immune response also displays direct tumor-promoting […]

Hans Selye and the 80th Birthday of Stress Research

Hans Selye and the 80th Birthday of Stress Research

Stress research has been around for 80 years but has perhaps never been more actual and trendy as in recent years. The term ‘stress’ (psychological) is extremely popular and the general public, as well as celebrities, frequently use and occasionally abuse this term to describe situations causing agitation or alteration of their wellbeing. In PubMed, […]

Donna Jackson Nakazawa and Childhood Disrupted: How Your Biography Becomes Your Biology and How You Can Heal

Donna Jackson Nakazawa and Childhood Disrupted: How Your Biography Becomes Your Biology and How You Can Heal

SHORT FEATURES and FACES ARTICLE Donna Jackson Nakazawa is an award-winning science journalist interested in exploring the intersection between neuroscience, immunology, and the deepest inner workings of the human heart. Her mission as a journalist is to weave together insights from lived, human experience with cutting edge science, and to translate these findings in ways […]

More Evidence that Norepinephrine and β3-Adrenoreceptors May Drive Melanoma Progression & Aggressiveness

More Evidence that Norepinephrine and β3-Adrenoreceptors May Drive Melanoma Progression & Aggressiveness

A report recently published in Oncotarget shows that the β3-adrenoreceptors are involved in melanoma aggressiveness, and that these receptors, expressed on several accessory cells, may orchestrate their function and thus, sustain melanoma progression. Recent research indicates that stress and stress mediators contribute to cancer development and/or progression. It appears that in this process a major […]

Psychoneuroimmunology: Stress, Mental Disorders and Health (Progress in Psychiatry)

Another excellent book devoted to the interdisciplinary area of research known as psychoneuroimmunology (PNI). The field bridges together psychiatry, neurology, neuroendocrinology and immunology. The book is the result of a collaborative work of many international experts including Cobi J. Heijnen, Pranela Rameshwar, Nancy G. Klimas and many others. Psychoneuroimmunology: Stress, Mental Disorders and Health deals […]

The Stress of Life

The Stress of Life, a classic book written by the man who introduced the term (psychological) “stress” and “dedicated his entire scientific career to furnish more and more proof for the importance of neuroendocrine mechanisms in the development of disease. János Hugo Bruno “Hans” Selye (January 26, 1907 – October 16, 1982) was a pioneering […]

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